A Novel Conus Snail Polypeptide Causes Excitotoxicity by Blocking Desensitization of AMPA Receptors

BACKGROUND: Ionotropic glutamate receptors (iGluRs) are glutamate-gated ion channels that mediate excitatory neurotransmission in the central nervous system. Based on both molecular and pharmacological criteria, iGluRs have been divided into two major classes, the non-NMDA-class, which includes both...

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Bibliografische gegevens
Hoofdauteurs: Walker, Craig S., Jensen, Stori, Ellison, Michael, Matta, Jose A., Lee, Won Yong, Imperial, Julita S., Duclos, Nick, Brockie, Penelope J., Madsen, David M., Isaac, John T. R., Olivera, Baldomero, Maricq, Andres V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722447/
https://ncbi.nlm.nih.gov/pubmed/19481459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.017
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