A Novel Conus Snail Polypeptide Causes Excitotoxicity by Blocking Desensitization of AMPA Receptors

BACKGROUND: Ionotropic glutamate receptors (iGluRs) are glutamate-gated ion channels that mediate excitatory neurotransmission in the central nervous system. Based on both molecular and pharmacological criteria, iGluRs have been divided into two major classes, the non-NMDA-class, which includes both...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Walker, Craig S., Jensen, Stori, Ellison, Michael, Matta, Jose A., Lee, Won Yong, Imperial, Julita S., Duclos, Nick, Brockie, Penelope J., Madsen, David M., Isaac, John T. R., Olivera, Baldomero, Maricq, Andres V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722447/
https://ncbi.nlm.nih.gov/pubmed/19481459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.017
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