Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

Toxoplasma gondii, as an obligate intracellular and promiscuous pathogen of mammalian cells, utilizes host sugars for energy and to generate glycoconjugates that are important to its survival and virulence. Here, we report that T. gondii glucose transporter (TgGT1) is proficient in transporting mann...

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Bibliographic Details
Main Authors: Blume, Martin, Rodriguez-Contreras, Dayana, Landfear, Scott, Fleige, Tobias, Soldati-Favre, Dominique, Lucius, Richard, Gupta, Nishith
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722337/
https://ncbi.nlm.nih.gov/pubmed/19617561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903831106
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