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Taming the tiger by the tail: modulation of DNA damage responses by telomeres

Telomeres are by definition stable and inert chromosome ends, whereas internal chromosome breaks are potent stimulators of the DNA damage response (DDR). Telomeres do not, as might be expected, exclude DDR proteins from chromosome ends but instead engage with many DDR proteins. However, the most pow...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Lydall, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722249/
https://ncbi.nlm.nih.gov/pubmed/19629039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.176
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