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PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders

Members of the peroxisome proliferator-activated receptor γ coactivator (PGC) family are potent inducers of mitochondrial biogenesis. We have tested the potential effect of increased mitochondrial biogenesis in cells derived from patients harboring oxidative phosphorylation defects due to either nuc...

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Detalhes bibliográficos
Main Authors: Srivastava, Sarika, Diaz, Francisca, Iommarini, Luisa, Aure, Karine, Lombes, Anne, Moraes, Carlos T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722224/
https://ncbi.nlm.nih.gov/pubmed/19297390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp093
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