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PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders
Members of the peroxisome proliferator-activated receptor γ coactivator (PGC) family are potent inducers of mitochondrial biogenesis. We have tested the potential effect of increased mitochondrial biogenesis in cells derived from patients harboring oxidative phosphorylation defects due to either nuc...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722224/ https://ncbi.nlm.nih.gov/pubmed/19297390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp093 |
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