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PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders

Members of the peroxisome proliferator-activated receptor γ coactivator (PGC) family are potent inducers of mitochondrial biogenesis. We have tested the potential effect of increased mitochondrial biogenesis in cells derived from patients harboring oxidative phosphorylation defects due to either nuc...

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Hlavní autoři: Srivastava, Sarika, Diaz, Francisca, Iommarini, Luisa, Aure, Karine, Lombes, Anne, Moraes, Carlos T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722224/
https://ncbi.nlm.nih.gov/pubmed/19297390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp093
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