Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk

A single nucleotide polymorphism (SNP) at 10q11 (rs10993994) in the 5′ region of the MSMB gene was recently implicated in prostate cancer risk in two genome-wide association studies. To identify possible causal variants in the region, we genotyped 16 tagging SNPs and imputed 29 additional SNPs in ∼6...

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Main Authors: Chang, Bao-Li, Cramer, Scott D., Wiklund, Fredrik, Isaacs, Sarah D., Stevens, Victoria L., Sun, Jielin, Smith, Shelly, Pruett, Kristen, Romero, Lina M., Wiley, Kathleen E., Kim, Seong-Tae, Zhu, Yi, Zhang, Zheng, Hsu, Fang-Chi, Turner, Aubrey R., Adolfsson, Jan, Liu, Wennuan, Kim, Jin Woo, Duggan, David, Carpten, John, Zheng, S. Lilly, Rodriguez, Carmen, Isaacs, William B., Grönberg, Henrik, Xu, Jianfeng
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Association Studies Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722195/
https://ncbi.nlm.nih.gov/pubmed/19153072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp035
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