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Requirements for prediction of peptide retention time in reversed-phase high-performance liquid chromatography: hydrophilicity/hydrophobicity of side-chains at the N- and C-termini of peptides are dramatically affected by the end-groups and location

The value of reversed-phase high-performance liquid chromatography (RP-HPLC) and the field of proteomics would be greatly enhanced by accurate prediction of retention times of peptides of known composition. The present study investigates the hydrophilicity/hydrophobicity of amino acid side-chains at...

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Detalhes bibliográficos
Main Authors: Tripet, Brian, Cepeniene, Dziuleta, Kovacs, James M., Mant, Colin T., Krokhin, Oleg V., Hodges, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722105/
https://ncbi.nlm.nih.gov/pubmed/17187811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2006.12.024
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