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Genome-Wide mRNA Expression Analysis of Hepatic Adaptation to High-Fat Diets Reveals Switch from an Inflammatory to Steatotic Transcriptional Program

BACKGROUND: Excessive exposure to dietary fats is an important factor in the initiation of obesity and metabolic syndrome associated pathologies. The cellular processes associated with the onset and progression of diet-induced metabolic syndrome are insufficiently understood. PRINCIPAL FINDINGS: To...

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Detalhes bibliográficos
Main Authors: Radonjic, Marijana, de Haan, Jorn R., van Erk, Marjan J., van Dijk, Ko Willems, van den Berg, Sjoerd A. A., de Groot, Philip J., Müller, Michael, van Ommen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722023/
https://ncbi.nlm.nih.gov/pubmed/19680557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006646
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