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Cocaine-induced hyperactivity and sensitization are dependent on GSK3

Glycogen synthase kinase 3 (GSK3) is a critical mediator of many intracellular signaling systems. The activity of GSK3 is regulated by several kinases, with inactivation occurring via phosphorylation of the inhibitory serine-21 (α-isoform) and serine-9 (β-isoform) residues. Here, we investigated whe...

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Detalhes bibliográficos
Main Authors: Miller, Jonathan S., Tallarida, Ronald J., Unterwald, Ellen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721824/
https://ncbi.nlm.nih.gov/pubmed/19328817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.03.006
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