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Endobrevin/VAMP-8–dependent dense granule release mediates thrombus formation in vivo

Individuals whose platelets lack dense or α-granules suffer various degrees of abnormal bleeding, implying that granule cargo contributes to hemostasis. Despite these clinical observations, little is known regarding the effects of impaired platelet granule secretion on thrombus formation in vivo. In...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Graham, Gwenda J., Ren, Qiansheng, Dilks, James R., Blair, Price, Whiteheart, Sidney W., Flaumenhaft, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721786/
https://ncbi.nlm.nih.gov/pubmed/19395672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210211
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