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Variation in bone morphogenetic protein 15 is not associated with spontaneous human dizygotic twinning

BACKGROUND: Spontaneous dizygotic (DZ) twinning in humans is under genetic control. In sheep, heterozygous loss of function mutations in bone morphogenetic protein 15 (BMP15) increase ovulation and hence twinning rates. METHODS: To investigate the role of BMP15 in human twinning, we typed 14 common...

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Main Authors: Zhao, Zhen Zhen, Painter, Jodie N., Palmer, James S., Webb, Penelope M., Hayward, Nicholas K., Whiteman, David C., Boomsma, Dorret I., Martin, Nicholas G., Duffy, David L., Montgomery, Grant W.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721723/
https://ncbi.nlm.nih.gov/pubmed/18614612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/den268
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