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Evidence that impurities contribute to the fluorescence of the polyene antibiotic amphotericin B

OBJECTIVES: Based on the assertion that fluorescence spectroscopy detects dimers of the polyene antibiotic amphotericin B (AmB), this technique was recently proposed to analyse the interaction of the drug with cell membranes. However, contradictory results indicate that this ‘dimeric’ fluorescence m...

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Bibliografiske detaljer
Main Authors: Bolard, Jacques, Cleary, John D., Kramer, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721696/
https://ncbi.nlm.nih.gov/pubmed/19258352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp059
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