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JP-8 Induces Immune Suppression via a Reactive Oxygen Species NF-κβ–Dependent Mechanism
Applying jet fuel (JP-8) to the skin of mice induces immune suppression. JP-8–treated keratinocytes secrete prostaglandin E(2), which is essential for activating immune suppressive pathways. The molecular pathway leading to the upregulation of the enzyme that controls prostaglandin synthesis, cycloo...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2009
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721654/ https://ncbi.nlm.nih.gov/pubmed/19095747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn262 |
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