Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer

There is evidence from both genetic and pharmacologic studies to suggest that the cyclooxygenase-2 (COX-2) enzyme plays a causal role in the development of colorectal cancer. However, little is known about the identity or role of the eicosanoid receptor pathways activated by COX-derived prostaglandi...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gupta, Rajnish A., Tan, Jian, Krause, Wade F., Geraci, Mark W., Willson, Timothy M., Dey, Sudhansu K., DuBois, Raymond N.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11087869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.24.13275
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