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Glomerular filtration is normal in the absence of both agrin and perlecan–heparan sulfate from the glomerular basement membrane

Background. For several decades, it has been thought that the glomerular basement membrane (GBM) provides a charge-selective barrier for glomerular filtration. However, recent evidence has presented challenges to this concept: selective removal of heparan sulfate (HS) moieties that impart a negative...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Goldberg, Seth, Harvey, Scott J., Cunningham, Jeanette, Tryggvason, Karl, Miner, Jeffrey H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721481/
https://ncbi.nlm.nih.gov/pubmed/19144998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfn758
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