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Glomerular filtration is normal in the absence of both agrin and perlecan–heparan sulfate from the glomerular basement membrane
Background. For several decades, it has been thought that the glomerular basement membrane (GBM) provides a charge-selective barrier for glomerular filtration. However, recent evidence has presented challenges to this concept: selective removal of heparan sulfate (HS) moieties that impart a negative...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721481/ https://ncbi.nlm.nih.gov/pubmed/19144998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfn758 |
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