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Combination of small interfering RNAs mediates greater suppression on hepatitis B virus cccDNA in HepG2.2.15 cells

AIM: To observe the inhibition of hepatitis B virus (HBV) replication and expression in HepG2.2.15 cells by combination of small interfering RNAs (siRNAs). METHODS: Recombinant plasmid psil-HBV was constructed and transfected into HepG2.2.15 cells. At 48 h, 72 h and 96 h after transfection, culture...

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Detalhes bibliográficos
Main Authors: Xin, Xiao-Min, Li, Gui-Qiu, Jin, Ying-Yu, Zhuang, Min, Li, Di
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721441/
https://ncbi.nlm.nih.gov/pubmed/18609708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.3849
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