Deregulation of Hepatic Insulin Sensitivity Induced by Central Lipid Infusion in Rats Is Mediated by Nitric Oxide

BACKGROUND: Deregulation of hypothalamic fatty acid sensing lead to hepatic insulin-resistance which may partly contribute to further impairment of glucose homeostasis. METHODOLOGY: We investigated here whether hypothalamic nitric oxide (NO) could mediate deleterious peripheral effect of central lip...

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Bibliographic Details
Main Authors: Marsollier, Nicolas, Kassis, Nadim, Mezghenna, Karima, Soty, Maud, Fioramonti, Xavier, Lacombe, Amélie, Joly, Aurélie, Pillot, Bruno, Zitoun, Carine, Vilar, José, Mithieux, Gilles, Gross, René, Lajoix, Anne-Dominique, Routh, Vanessa, Magnan, Christophe, Cruciani-Guglielmacci, Céline
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721417/
https://ncbi.nlm.nih.gov/pubmed/19680547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006649
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