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The molecular genetics of breast cancer and targeted therapy

Breast cancer is a complex, molecular disease, in which a number of cellular pathways involving cell growth and proliferation, such as the MAPK, RB/E2F, P13K/AKT/mTOR, and TP53 pathways, are altered. These pathways represent molecular mechanisms that are composed and regulated by various genes. The...

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Detalhes bibliográficos
Main Authors: Suter, Rachel, Marcum, James A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721311/
https://ncbi.nlm.nih.gov/pubmed/19707334
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