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Drug focus: adalimumab in the treatment of moderate to severe psoriasis

Adalimumab is a fully human IgG1 monoclonal antibody that specifically binds to tumor necrosis factor (TNF)-alpha, and is administered by subcutaneous injection. The mechanism of action is based on both the neutralization of TNF-alpha bioactivity and the induction of apoptosis of TNF-expressing mono...

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Autors principals: Vena, Gino A, Cassano, Nicoletta
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721299/
https://ncbi.nlm.nih.gov/pubmed/19707319
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