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Review of erlotinib in the treatment of advanced non-small cell lung cancer

Epidermal growth factor receptor (EGFR) is a transmembrane receptor with a cytoplasmic tyrosine kinase (TK) domain present on many solid tumors including non-small cell lung cancer (NSCLC). Once stimulated by ligand, the downstream pathway is activated leading to cell growth, survival, and carcinoge...

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Detalhes bibliográficos
Main Authors: Ganjoo, Kristen N, Wakelee, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721286/
https://ncbi.nlm.nih.gov/pubmed/19707304
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