Comprehensive evaluation of a novel nuclear factor-κB inhibitor, quinoclamine, by transcriptomic analysis

BACKGROUND AND PURPOSE: The transcription factor nuclear factor-κB (NF-κB) has been linked to the cell growth, apoptosis and cell cycle progression. NF-κB blockade induces apoptosis of cancer cells. Therefore, NF-κB is suggested as a potential therapeutic target for cancer. Here, we have evaluated t...

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Detalhes bibliográficos
Main Authors: Cheng, W-Y, Lien, J-C, Hsiang, C-Y, Wu, S-L, Li, C-C, Lo, H-Y, Chen, J-C, Chiang, S-Y, Liang, J-A, Ho, T-Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721260/
https://ncbi.nlm.nih.gov/pubmed/19422389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00223.x
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