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Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin
Down syndrome critical region 1 (DSCR1), an oxidative stress-response gene, interacts with calcineurin and represses its phosphatase activity. Recently it was shown that hydrogen peroxide inactivates calcineurin by proteolytic cleavage. Based on these facts, we investigated whether oxidative stress...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korean Society of Medical Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721144/ https://ncbi.nlm.nih.gov/pubmed/19322033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.7.052 |
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