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Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin

Down syndrome critical region 1 (DSCR1), an oxidative stress-response gene, interacts with calcineurin and represses its phosphatase activity. Recently it was shown that hydrogen peroxide inactivates calcineurin by proteolytic cleavage. Based on these facts, we investigated whether oxidative stress...

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Detalhes bibliográficos
Main Authors: Lee, Ji-Eun, Jang, Hyonchol, Cho, Eun-Jung, Youn, Hong-Duk
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721144/
https://ncbi.nlm.nih.gov/pubmed/19322033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.7.052
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