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Posttranslational modification of the glycosylation inhibiting factor (GIF) gene product generates bioactive GIF

Glycosylation inhibiting factor (GIF) and macrophage migration inhibitory factor (MIF) share an identical structure gene. Here we unravel two steps of posttranslational modifications in GIF/MIF molecules in human suppressor T (Ts) cell hybridomas. Peptide mapping and MS analysis of the affinity-puri...

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Main Authors: Watarai, Hiroshi, Nozawa, Risa, Tokunaga, Ayako, Yuyama, Noriko, Tomas, Mayumi, Hinohara, Atsushi, Ishizaka, Kimishige, Ishii, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC27211/
https://ncbi.nlm.nih.gov/pubmed/11069294
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