A carregar...

Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo

Ras signaling can promote proliferation, cell survival and differentiation. Mutations in components of the Ras pathway are found in many solid tumors and are associated with developmental disorders. We demonstrate here that Drosophila tissues containing hypomorphic mutations in E1, the most upstream...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yan, Hua, Chin, Mei-Ling, Horvath, Elizabeth A., Kane, Elizabeth A., Pfleger, Cathie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721006/
https://ncbi.nlm.nih.gov/pubmed/19366732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.042267
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!