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Endocytic trafficking of activated EGFR is AP-2 dependent and occurs through preformed clathrin spots
The removal of the epidermal growth factor receptor (EGFR) from the cell surface by endocytosis is triggered by receptor activation, but many facets of EGFR trafficking remain unresolved. We employed total internal fluorescence microscopy to elucidate the dynamics of activated EGFR at the cell surfa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721002/ https://ncbi.nlm.nih.gov/pubmed/19351721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.040030 |
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