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Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling

Increases in reactive oxygen species (ROS) have been implicated in age-related diseases, including cancer. The serine/threonine kinase protein kinase D1 (PKD1) is a stress-responsive kinase and sensor for reactive oxygen species, which can initiate cell survival through NF-κB signaling. We have prev...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cowell, Catherine F., Döppler, Heike, Yan, Irene K., Hausser, Angelika, Umezawa, Yoshio, Storz, Peter
פורמט: Artigo
שפה:Inglês
יצא לאור: Company of Biologists 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720927/
https://ncbi.nlm.nih.gov/pubmed/19258390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.041061
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