Induction of Apoptosis in Human Cancer Cells by Candidaspongiolide, a Novel Sponge Polyketide

BACKGROUND: Candidaspongiolide (CAN), a novel polyketide from a marine sponge, is the active component of a mixture that was found to be potently cytotoxic in the National Cancer Institute’s 60-cell-line screen. METHODS: Effects of CAN on U251 glioma and HCT116 colorectal cancer cells and on normal...

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Main Authors: Trisciuoglio, Daniela, Uranchimeg, Badarch, Cardellina, John H., Meragelman, Tamara L., Matsunaga, Shigeki, Fusetani, Nobuhiru, Del Bufalo, Donatella, Shoemaker, Robert H., Melillo, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720712/
https://ncbi.nlm.nih.gov/pubmed/18728285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn239
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