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Mascot-derived False Positive Peptide Identifications Revealed by Manual Analysis of Tandem Mass Spectra

False positives that arise when MS/MS data are used to search protein sequence databases remain a concern in proteomics research. Here we present five types of false positives identified when aligning sequences to MS/MS spectra by Mascot database searching software. False positives arise because of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Yue, Zhang, Junmei, Xing, Gang, Zhao, Yingming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720604/
https://ncbi.nlm.nih.gov/pubmed/19368407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900172v
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