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Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy

New inhibitors are urgently needed to overcome the burgeoning problem of drug resistance in the treatment of Plasmodium falciparum infection. Targeting the folate pathway has proved to be a powerful strategy for drug development against rapidly multiplying systems such as cancer cells and microorgan...

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Bibliografiska uppgifter
Huvudupphovsmän: Nzila, Alexis, Ward, Steve A., Marsh, Kevin, Sims, Paul F.G., Hyde, John E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720520/
https://ncbi.nlm.nih.gov/pubmed/15922251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2005.04.002
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