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Spatial Patterning of Cell Proliferation and Differentiation Depends on Mechanical Stress Magnitude

Mechanical stress has been proposed as a major regulator of tissue morphogenesis; however, it remains unclear what is the exact mechanical signal that leads to local tissue pattern formation. We explored this question by using a micropatterned cell aggregate model in which NIH 3T3 fibroblasts were c...

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Autors principals: Li, Bin, Li, Fang, Puskar, Kathleen M., Wang, James H-C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720430/
https://ncbi.nlm.nih.gov/pubmed/19482284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2009.04.033
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