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A possible effector role for the pleckstrin homology (PH) domain of dynamin
The large GTPase dynamin plays a key role in clathrin-mediated endocytosis in animal cells, although its mechanism of action remains unclear. Dynamins 1, 2, and 3 contain a pleckstrin homology (PH) domain that binds phosphoinositides with a very low affinity (K(D) > 1 mM), and this interaction ap...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720410/ https://ncbi.nlm.nih.gov/pubmed/19666604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906945106 |
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