The human sex-reversing ATRX gene has a homologue on the marsupial Y chromosome, ATRY: Implications for the evolution of mammalian sex determination

Mutations in the ATRX gene on the human X chromosome cause X-linked α-thalassemia and mental retardation. XY patients with deletions or mutations in this gene display varying degrees of sex reversal, implicating ATRX in the development of the human testis. To explore further the role of ATRX in mamm...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Pask, Andrew, Renfree, Marilyn B., Marshall Graves, Jennifer A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11069290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230424497
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