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Loop residues of the receptor binding domain of Bacillus thuringiensis Cry11Ba toxin are important for mosquitocidal activity

Using a Cry11Ba toxin model, predicted loops in domain II were analyzed for their role in receptor binding and toxicity. Peptides corresponding to loops α8, 1 and 3, but not loop 2, competed with toxin binding to Aedes midgut membranes. Mutagenesis data reveal loops α8, 1 and 3 are involved in toxic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Likitvivatanavong, Supaporn, Aimanova, Karlygash, Gill, Sarjeet S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720071/
https://ncbi.nlm.nih.gov/pubmed/19450583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.05.020
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