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Scn2a Sodium Channel Mutation Results in Hyperexcitability in the Hippocampus in vitro

PURPOSE: To investigate in vitro, the cellular network activity of the hippocampus in Q54 mice that display spontaneous seizures because of a gain-of-function mutation of the Scn2a sodium channel gene. METHODS: Extacellular recordings were obtained from CA1 and CA3 pyramidal neurons in hippocampal s...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kile, Kara Buehrer, Tian, Nan, Durand, Dominique M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720056/
https://ncbi.nlm.nih.gov/pubmed/18031550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2007.01413.x
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