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Scn2a Sodium Channel Mutation Results in Hyperexcitability in the Hippocampus in vitro
PURPOSE: To investigate in vitro, the cellular network activity of the hippocampus in Q54 mice that display spontaneous seizures because of a gain-of-function mutation of the Scn2a sodium channel gene. METHODS: Extacellular recordings were obtained from CA1 and CA3 pyramidal neurons in hippocampal s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720056/ https://ncbi.nlm.nih.gov/pubmed/18031550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2007.01413.x |
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