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Genomic amplicons target vesicle recycling in breast cancer

Aberrant endocytosis, vesicle targeting, and receptor recycling represent emerging hallmarks of cancer. In this issue of the JCI, Zhang and colleagues demonstrate that RAB-coupling protein (RCP; also known as RAB11FIP1) is a “driver” of the 8p11–12 amplicon in human breast cancer and mouse xenograft...

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Detalhes bibliográficos
Main Authors: Mills, Gordon B., Jurisica, Igor, Yarden, Yosef, Norman, Jim C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719927/
https://ncbi.nlm.nih.gov/pubmed/19620778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40256
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