A Novel Combination of Factors, Termed SPIE, which Promotes Dopaminergic Neuron Differentiation from Human Embryonic Stem Cells

BACKGROUND: Stromal-Derived Inducing Activity (SDIA) is one of the most efficient methods of generating dopaminergic (DA) neurons from embryonic stem cells (ESC). DA neuron induction can be achieved by co-culturing ESC with the mouse stromal cell lines PA6 or MS5. The molecular nature of this effect...

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Autores principales: Vazin, Tandis, Becker, Kevin G., Chen, Jia, Spivak, Charles E., Lupica, Carl R., Zhang, Yongqing, Worden, Lila, Freed, William J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719871/
https://ncbi.nlm.nih.gov/pubmed/19672298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006606
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