Incorporation of NKT cell activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis BCG

The attenuated strain of Mycobacterium bovis known as bacille Calmette-Guérin (BCG) has been widely used as a vaccine for prevention of disease by Mycobacterium tuberculosis, but with relatively little evidence of success. Recent studies suggest that the failure of BCG may be due to its retention of...

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Huvudupphovsmän: Venkataswamy, Manjunatha. M., Baena, Andres, Goldberg, Michael F., Bricard, Gabriel, Im, Jin S., Chan, John, Reddington, Faye, Besra, Gurdyal S., Jacobs, William R., Porcelli, Steven A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719834/
https://ncbi.nlm.nih.gov/pubmed/19620317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900858
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