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T cell receptor signaling and immunological synapse stability require myosin IIA

Immunological synapses are initiated by signaling in discrete T cell receptor (TCR) microclusters and play an important role in T cell differentiation and effector functions. Synapse formation involves orchestrated motion of microclusters toward the center of the contact area with the antigen-presen...

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Bibliographic Details
Main Authors: Ilani, Tal, Vasiliver-Shamis, Gaia, Vardhana, Santosh, Bretscher, Anthony, Dustin, Michael L.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719775/
https://ncbi.nlm.nih.gov/pubmed/19349987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1723
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