Evaluation of Tracer Kinetic Models for Analysis of [(18)F]FDDNP Studies

PURPOSE: Different pharmacokinetic methods for [(18)F]FDDNP studies were evaluated using both simulations and clinical data. PROCEDURES: Methods included two-tissue reversible plasma (2T4k), simplified reference tissue input (SRTM), and a modified 2T4k models. The latter included an additional compa...

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Main Authors: Yaqub, Maqsood, Boellaard, Ronald, van Berckel, Bart N. M., Tolboom, Nelleke, Luurtsema, Gert, Dijkstra, Anke A., Lubberink, Mark, Windhorst, Albert D., Scheltens, Philip, Lammertsma, Adriaan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719728/
https://ncbi.nlm.nih.gov/pubmed/19340487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-009-0208-1
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