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Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles

Hepatitis C virus (HCV) is an enveloped, positive strand RNA virus of about 9.6 kb. Like all enveloped viruses, the HCV membrane fuses with the host cell membrane during the entry process and thereby releases the genome into the cytoplasm, initiating the viral replication cycle. To investigate the f...

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Bibliografiska uppgifter
Huvudupphovsmän: Haid, Sibylle, Pietschmann, Thomas, Pécheur, Eve-Isabelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719405/
https://ncbi.nlm.nih.gov/pubmed/19411248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014647
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