Structural Requirements for the Ubiquitin-associated Domain of the mRNA Export Factor Mex67 to Bind Its Specific Targets, the Transcription Elongation THO Complex Component Hpr1 and Nucleoporin FXFG Repeats

The ubiquitin-associated (UBA) domain of the principal Saccharomyces cerevisiae mRNA nuclear export factor, Mex67, can bind both nuclear pore protein (nucleoporin) FG repeats and Hpr1, a component of the TREX·THO complex that functions to link transcription and export. Using fluorescence resonance e...

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Main Authors: Hobeika, Maria, Brockmann, Christoph, Gruessing, Florian, Neuhaus, David, Divita, Gilles, Stewart, Murray, Dargemont, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719396/
https://ncbi.nlm.nih.gov/pubmed/19401465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004374
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