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Mechanism of Inhibition by C-terminal α-Helices of the ϵ Subunit of Escherichia coli F(o)F(1)-ATP Synthase

The ϵ subunit of bacterial F(o)F(1)-ATP synthase (F(o)F(1)), a rotary motor protein, is known to inhibit the ATP hydrolysis reaction of this enzyme. The inhibitory effect is modulated by the conformation of the C-terminal α-helices of ϵ, and the “extended” but not “hairpin-folded” state is responsib...

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Detalhes bibliográficos
Main Authors: Iino, Ryota, Hasegawa, Rie, Tabata, Kazuhito V., Noji, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719386/
https://ncbi.nlm.nih.gov/pubmed/19411254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003798
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