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Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk
Interaction of TCF7l2 with translocated β-catenin in the nucleus transiently converts TCF7L2 to transcription factor activators, which induce the expression of target genes, including cyclin D1 and c-myc, in colorectal carcinogenesis. We evaluated the association of a polymorphism in TCF7L2 (RS12255...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719293/ https://ncbi.nlm.nih.gov/pubmed/18478343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-008-9164-3 |
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