Negundoside, an iridiod glycoside from leaves of Vitex negundo, protects human liver cells against calcium-mediated toxicity induced by carbon tetrachloride

AIM: To evaluate the protective effect of 2'-p-hydroxybenzoylmussaenosidic acid [negundoside (NG), against carbon tetrachloride (CCl(4))-induced toxicity in HuH-7 cells. METHODS: CCl(4) is a well characterized hepatotoxin, and inducer of cytochrome P450 2E1 (CYP2E1)-mediated oxidative stress. I...

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Detalhes bibliográficos
Main Authors: Tasduq, Sheikh A, Kaiser, Peerzada J, Gupta, Bishan D, Gupta, Vijay K, Johri, Rakesh K
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719232/
https://ncbi.nlm.nih.gov/pubmed/18595136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.3693
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