Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B(12) status

AIM: To evaluate joint effects of Methylentetrahydrofolate reductase (MTHFR) C677T genotypes, and serum folate/vitamin B(12) concentrations on promoter methylation of tumor-associated genes among Iranian colorectal cancer patients. METHODS: We examined the associations between MTHFR C677T genotype,...

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Detalhes bibliográficos
Main Authors: Mokarram, Pooneh, Naghibalhossaini, Fakhraddin, Firoozi, Mehdi Saberi, Hosseini, Seyed Vahid, Izadpanah, Ahmad, Salahi, Heshmetalah, Malek-Hosseini, Seyed Ali, Talei, Abdoulrasool, Mojallal, Mehra
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719229/
https://ncbi.nlm.nih.gov/pubmed/18595133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.3662
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