Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease

Glioblastoma multiforme (GBM) is a lethal primary malignant brain tumor in adults. R115777 (tipifarnib) is an oral agent with antiproliferative effects, being a potent and selective inhibitor of farnesyltransferase. This multicenter, open-label phase II study was designed to evaluate the efficacy an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lustig, Robert, Mikkelsen, Tom, Lesser, Glenn, Grossman, Stuart, Ye, Xiaobu, Desideri, Serena, Fisher, Joy, Wright, John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Duke University Press 2008
Pynciau:
Clinical Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718997/
https://ncbi.nlm.nih.gov/pubmed/18725460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-070
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