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AMPA receptors promote perivascular glioma invasion via β1 integrin–dependent adhesion to the extracellular matrix
High-grade gliomas release excitotoxic concentrations of glutamate, which has been shown to enhance tumor proliferation and migration. α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) glutamate receptors are abundantly expressed at the invading edge of glioblastoma specimens, suggesting t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Duke University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718970/ https://ncbi.nlm.nih.gov/pubmed/18957620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-094 |
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