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OHMM: a Hidden Markov Model accurately predicting the occupancy of a transcription factor with a self-overlapping binding motif

BACKGROUND: DNA sequence binding motifs for several important transcription factors happen to be self-overlapping. Many of the current regulatory site identification methods do not explicitly take into account the overlapping sites. Moreover, most methods use arbitrary thresholds and fail to provide...

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Autors principals: Drawid, Amar, Gupta, Nupur, Nagaraj, Vijayalakshmi H, Gélinas, Céline, Sengupta, Anirvan M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718928/
https://ncbi.nlm.nih.gov/pubmed/19583839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-208
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