Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

Viruses are obligate intracellular parasites and therefore their replication completely depends on host cell factors. In case of the hepatitis C virus (HCV), a positive-strand RNA virus that in the majority of infections establishes persistence, cyclophilins are considered to play an important role...

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Main Authors: Kaul, Artur, Stauffer, Sarah, Berger, Carola, Pertel, Thomas, Schmitt, Jennifer, Kallis, Stephanie, Zayas Lopez, Margarita, Lohmann, Volker, Luban, Jeremy, Bartenschlager, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718831/
https://ncbi.nlm.nih.gov/pubmed/19680534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000546
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